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Inovio Pharmaceuticals stock jumps 190.83% as hourly RSI reaches 82.54

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Inovio Pharmaceuticals stock carries a bullish daily bias, yet its trend structure is not fully aligned. Price stands above all three daily exponential averages and above the upper Bollinger band. At the same time, overbought hourly and 15-minute readings complicate the near-term picture.

INO — daily chart with candlesticks, EMA20/EMA50 and volume.

Key takeaways

INO was trading at $1.745 as of 10:08 ET, within a session range of $1.66 to $1.99.

The intraday gain was 190.83% versus the previous close, on volume of 872,426 shares so far.

The daily RSI14 is 69.35, up from 27.05, above 50 and below the overbought threshold of 70.

Price stands above the daily upper Bollinger band at $1.44 and above the 20-session, 50-session and 200-session EMAs at $1.02, $1.07 and $1.33.

Hourly RSI14 is 82.54 and 15-minute RSI14 is 89.81, both above the 70 threshold; the 15-minute pivot is $1.73, with R1 at $1.8 and S1 at $1.67.

On Monday, November 2, 2026, INO opened at $1.99, traded between a low of $1.66 and a high of $1.99, and was trading at $1.745 as of 10:08 ET. The intraday gain was 190.83% versus the previous close, with volume of 872,426 shares so far. INO opened at $1.99, traded between a low of $1.66 and a high of $1.99, and was last at $1.75, against a previous close of $0.60.

Meanwhile, a report published on October 30, 2026 carried INOVIO’s announcement of FDA accelerated approval for VOCERYQ , ahead of Monday’s session. The immunotherapy is intended to reduce the frequency of surgery in adults with recurrent respiratory papillomatosis.

Inovio Pharmaceuticals stock: daily strength without full trend alignment

The daily chart provides the strongest support for the bullish case, yet the averages are not stacked in bullish order. Price is above the 20-session EMA at $1.02, the 50-session EMA at $1.07 and the 200-session EMA at $1.33.

However, the 20-session average remains below the 50-session average, which sits below the 200-session average. That ordering does not constitute a fully aligned bullish trend for Inovio Pharmaceuticals stock.

Daily RSI14 rose to 69.35 from 27.05. It therefore sits above 50 but below the overbought threshold of 70. The daily MACD histogram increased to 0.04 from -0.03, and the MACD line at -0.03 holds above its signal at -0.07. Momentum evidence is therefore bullish even though the line remains negative.

Notably, price stands above the daily upper Bollinger band at $1.44 , outside the current daily envelope. Daily ATR14 increased to $0.22 from $0.13, indicating greater absolute volatility. The daily pivot, calculated from the previous completed daily candle, sits at $0.69, also below the current price.

Hourly confirmation comes with an overbought qualification

The hourly chart supports the daily price position, although its averages are not bullishly aligned either. Price stands above the 20-hour EMA at $0.86, the 50-hour EMA at $0.88 and the 200-hour EMA at $1.03. It also holds above the hourly upper Bollinger band at $1.31 and the hourly pivot at $0.61.

At the same time, hourly RSI14 rose to 82.54 from 21.01 and now reads above the 70 threshold. The hourly MACD line at 0.02 stands above its signal at -0.03, with a positive histogram of 0.05. The conflict is therefore between bullish momentum evidence and an overbought reading, not between opposing directional signals.

Short-term levels frame the two scenarios

The 15-minute readings are overbought, while price trades above the short-term pivot at $1.73. On that timeframe, RSI14 is 89.81 , also above the 70 threshold. Its MACD line at 0.17 is above the signal at 0.04, while price holds above the upper Bollinger band at $1.59. The 15-minute ATR14 reads $0.12. These readings describe short-term conditions, not a separate primary trend.

Bullish case: holding $1.73 and clearing $1.8

The bullish scenario requires price to hold above the 15-minute pivot at $1.73 and to clear its first resistance, R1, at $1.8 . A move above the session high at $1.99 would provide further price confirmation. Continued positioning above the daily upper band at $1.44 would support that case.

Bearish case: a break below $1.73

Conversely, a break below the 15-minute pivot at $1.73 would weaken the immediate bullish setup. The next references are the 15-minute first support, S1, at $1.67 , then the session low at $1.66. Below those levels, the 15-minute upper band at $1.59 and the daily upper band at $1.44 become relevant. A break below the daily 200-session EMA at $1.33 would undermine the broader bullish case.

Overall, Inovio Pharmaceuticals stock stands above the 15-minute pivot at $1.73 but below resistance at $1.8 and the session high at $1.99. Daily ATR14 now reads $0.22, while daily RSI14 at 69.35 is approaching overbought territory and intraday RSI readings are above 70. Whether price can sustain its position above the daily averages remains unresolved during the open session.

FAQ

Where is Inovio Pharmaceuticals stock trading during Monday’s session?

INO was trading at $1.745 as of 10:08 ET, after opening at $1.99 and trading between a low of $1.66 and a high of $1.99.

Is the daily trend fully aligned for Inovio Pharmaceuticals stock?

No. Price is above the 20-session EMA at $1.02, the 50-session EMA at $1.07 and the 200-session EMA at $1.33. Still, the 20-session average remains below the 50-session average, which sits below the 200-session average.

What are the key short-term levels?

The 15-minute pivot is $1.73, with first resistance, R1, at $1.8 and first support, S1, at $1.67. The session low is $1.66 and the session high is $1.99.

What do the intraday RSI readings show?

Hourly RSI14 is 82.54 and 15-minute RSI14 is 89.81, both above the 70 threshold. The daily RSI14 is 69.35, above 50 and below 70.

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Disclaimer: This article is for informational purposes only and does not constitute financial advice, an investment recommendation, or a solicitation to buy or sell any financial instrument. The analysis provided is not indicative of future results. Investing in financial markets carries a high risk of capital loss. Always do your own research (DYOR) and consult a qualified financial advisor before making any decision.

Cryptonomist and the author hold no positions in the financial instruments mentioned and receive no compensation from the companies covered.

Article produced with the assistance of artificial intelligence and reviewed by the editorial team.

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